The first public molecular recognition database, BindingDB supports research, education and practice in drug discovery, pharmacology and related fields.

BindingDB contains 3.1M data for 1.3M Compounds and 9.6K Targets. Of those, 1.5M data for 708K Compounds and 4.7K Targets were curated by BindingDB curators. BindingDB is a FAIRsharing resource.

If BindingDB was of value to your research, please take a moment to donate to this nonprofit project. Your donation will let us provide you with more data and improved service.

To help with training and testing AI and other models, BindingDB downloads and search results now provide the publication date and BindingDB curation date of each measurement.

25 articles for thisTarget


The following articles (labelled with PubMed ID or TBD) are for your review

PMID
Data
Article Title
Organization
Discovery of N-(4-Fluoro-3-methoxybenzyl)-6-(2-(((2S,5R)-5-(hydroxymethyl)-1,4-dioxan-2-yl)methyl)-2H-tetrazol-5-yl)-2-methylpyrimidine-4-carboxamide. A Highly Selective and Orally Bioavailable Matrix Metalloproteinase-13 Inhibitor for the Potential Treatment of Osteoarthritis.EBI
Pfizer
Organic anion transporter 3 interacts selectively with lipophilicß-lactam antibiotics.EBI
Wilkes University
Evaluation and prediction of potential drug-drug interactions of linagliptin using in vitro cell culture methods.EBI
Nippon Boehringer Ingelheim
Characterization of methotrexate transport and its drug interactions with human organic anion transporters.EBI
Kyorin University
Interaction of human organic anion transporters with various cephalosporin antibiotics.EBI
Kyorin University
Characterization of organic anion transport inhibitors using cells stably expressing human organic anion transporters.EBI
Kyorin University
Functional involvement of rat organic anion transporter 3 (rOat3; Slc22a8) in the renal uptake of organic anions.EBI
University of Tokyo
Characterization of the efflux transport of 17beta-estradiol-D-17beta-glucuronide from the brain across the blood-brain barrier.EBI
The University of Tokyo
Interactions of human organic anion as well as cation transporters with indoxyl sulfate.EBI
Nagoya University School of Medicine
Human organic anion transporter 3 (hOAT3) can operate as an exchanger and mediate secretory urate flux.EBI
Georg-August-Universit£T
Different transport properties between famotidine and cimetidine by human renal organic ion transporters (SLC22A).EBI
Kyoto University Hospital
Interactions of human- and rat-organic anion transporters with pravastatin and cimetidine.EBI
Kyorin University
alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) antagonists: from bench to bedside.EBI
Novartis Pharma
Discovery and Optimization of Biaryl Alkyl Ethers as a Novel Class of Highly Selective, CNS-Penetrable, and Orally Active Adaptor Protein-2-Associated Kinase 1 (AAK1) Inhibitors for the Potential Treatment of Neuropathic Pain.EBI
Bristol-Myers Squibb
Discovery of (EBI
Bristol-Myers Squibb
Identification of 2,2-Dimethylbutanoic Acid (HST5040), a Clinical Development Candidate for the Treatment of Propionic Acidemia and Methylmalonic Acidemia.EBI
Hemoshear Therapeutics
Discovery of Pamiparib (BGB-290), a Potent and Selective Poly (ADP-ribose) Polymerase (PARP) Inhibitor in Clinical Development.EBI
TBA
Optimizing the Benefit/Risk of Acetyl-CoA Carboxylase Inhibitors through Liver Targeting.EBI
Pfizer
Pharmacological urate-lowering approaches in chronic kidney disease.EBI
West China Hospital of Sichuan University
Dihydrophenanthrenes from Juncus effusus as Inhibitors of OAT1 and OAT3.EBI
Tianjin University
Involvement of rat organic anion transporter 3 (rOAT3) in cephaloridine-induced nephrotoxicity: in comparison with rOAT1.EBI
Kyorin University School of Medicine
Characterization of ochratoxin A transport by human organic anion transporters.EBI
Kyorin University
Expression and functional characterization of rat organic anion transporter 3 (rOat3) in the choroid plexus.EBI
University of Tokyo
Characterization of uremic toxin transport by organic anion transporters in the kidney.EBI
University of Tokyo
SERIES OF PIPERIDINE-SUBSTITUTED BENZOIC ACID COMPOUNDS, AND USE THEREOFBDB
Medshine Discovery