39 articles for thisTarget
The following articles (labelled with PubMed ID or TBD) are for your review
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Article Title
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Synthesis and biological evaluation of thiazole derivatives as novel USP7 inhibitors.
China Pharmaceutical University
X-ray structural and biological evaluation of a series of potent and highly selective inhibitors of human coronavirus papain-like proteases.
Purdue University
Spongiacidin C, a pyrrole alkaloid from the marine sponge Stylissa massa, functions as a USP7 inhibitor.
Kumamoto University
Selective Dual Inhibitors of the Cancer-Related Deubiquitylating Proteases USP7 and USP47.
TBA
Inhibition of BET recruitment to chromatin as an effective treatment for MLL-fusion leukaemia.
University of Cambridge
NVP-BHG712: Effects of Regioisomers on the Affinity and Selectivity toward the EPHrin Family.
Johann Wolfgang Goethe University
Discovery of pyrrolo[2,3-d]pyrimidin-4-one derivative YCH3124 as a potent USP7 inhibitor for cancer therapy.
Shanghai Institute of Materia Medica
Recent advances in the development of deubiquitinases inhibitors as antitumor agents.
China Pharmaceutical University
Discovery of potent small molecule ubiquitin-specific protease 10 inhibitors with anti-hepatocellular carcinoma activity through regulating YAP expression.
Zhejiang University
Triazole-fused pyrimidines in target-based anticancer drug discovery.
Zhenzhou University
Covalent Small Molecule Immunomodulators Targeting the Protease Active Site.
National Cancer Institute
Blocking Non-enzymatic Functions by PROTAC-Mediated Targeted Protein Degradation.
Second Military Medical University (Naval Medical University)
Recent advances in the development of ubiquitin-specific-processing protease 7 (USP7) inhibitors.
Zhengzhou University
A perspective on medicinal chemistry approaches towards adenomatous polyposis coli and Wnt signal based colorectal cancer inhibitors.
Gitam (Deemed To Be University)
Discovery of Potent Small-Molecule USP8 Inhibitors for the Treatment of Breast Cancer through Regulating ERα Expression.
China Pharmaceutical University
Discovery of Potent OTUB1/USP8 Dual Inhibitors Targeting Proteostasis in Non-Small-Cell Lung Cancer.
Fudan University
Design, synthesis, biological evaluation and structure-activity relationship study of quinazolin-4(3H)-one derivatives as novel USP7 inhibitors.
Zhengzhou University
N-benzylpiperidinol derivatives as novel USP7 inhibitors: Structure-activity relationships and X-ray crystallographic studies.
China Pharmaceutical University
Discovery of Potent, Selective, and Orally Bioavailable Inhibitors of USP7 with In Vivo Antitumor Activity.
Rapt Therapeutics
Advances in Discovering Deubiquitinating Enzyme (DUB) Inhibitors.
Dana-Farber Cancer Institute
Identification and Structure-Guided Development of Pyrimidinone Based USP7 Inhibitors.
Almac Discovery
Sulawesins A-C, Furanosesterterpene Tetronic Acids That Inhibit USP7, from a Psammocinia sp. Marine Sponge.
Kumamoto University
Pyrrolo[2,1-f][1,2,4]triazines: From C-nucleosides to kinases and back again, the remarkable journey of a versatile nitrogen heterocycle.
Teva Global R&D
Chemical Approaches to Intervening in Ubiquitin Specific Protease 7 (USP7) Function for Oncology and Immune Oncology Therapies.
Progenra
Discovery of Small-Molecule Inhibitors of Ubiquitin Specific Protease 7 (USP7) Using Integrated NMR and in Silico Techniques.
Genentech
1-pyridazin-/triazin-3-yl-piper(-azine)/idine/pyrolidine derivatives and compositions thereof for inhibiting the activity of SHP2
Novartis
Fused heterocyclic ring compounds and method of treating retinal disease using same
The Industry & Academic Cooperation In Chungnam National University (IAC)