BDBM707355 US20240408064, Compound 10097
SMILES CN(C)CC(=O)Nc1cccc(NC(=O)Cc2c[nH]c3cc(F)ccc23)c1
InChI Key InChIKey=JXYPVQVNFOBGOQ-UHFFFAOYSA-N
Data 4 Kd
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 707355
TargetGTPase HRas [G12V,1-166]/Son of sevenless homolog 1 [564-1049](Homo sapiens (Human))
Genetolead
US Patent
Genetolead
US Patent
Affinity DataKd: 108nMAssay Description:Dissociation constants were obtained by monitoring changes in chemical shifts as a function of ligand concentration. The changes in chemical shifts (...More data for this Ligand-Target Pair
TargetGTPase HRas [G12V,1-166]/Son of sevenless homolog 1 [564-1049](Homo sapiens (Human))
Genetolead
US Patent
Genetolead
US Patent
Affinity DataKd: 7.40E+4nMAssay Description:MST experiments were performed with a Monolith NT.115 Pico (NanoTemper Technologies, Munich, Germany). Fluorescence labeling of GDP-HRasG12V was achi...More data for this Ligand-Target Pair
TargetGTPase HRas [G12V,1-166]/Son of sevenless homolog 1 [564-1049](Homo sapiens (Human))
Genetolead
US Patent
Genetolead
US Patent
Affinity DataKd: 3.10E+4nMAssay Description:ITC experiments were performed using a Nano ITC isothermal titration calorimeter from TA Instruments. Experiments were performed in reverse-mode by t...More data for this Ligand-Target Pair
TargetGTPase HRas [G12V,1-166]/Son of sevenless homolog 1 [564-1049](Homo sapiens (Human))
Genetolead
US Patent
Genetolead
US Patent
Affinity DataKd: 8.80E+4nMAssay Description:SPR experiments were performed using the P4SPR from Affinité Instruments using Ni-NTA immobilization chips and his-tagged protein. Ni-NTA coated surf...More data for this Ligand-Target Pair