BindingDB

The first public molecular recognition database, BindingDB supports research, education and practice in drug discovery, pharmacology and related fields.

BindingDB contains 3.1M data for 1.4M Compounds and 9.6K Targets. Of those, 1.5M data for 718K Compounds and 4.7K Targets were curated by BindingDB curators. BindingDB is a FAIRsharing resource.

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14 articles for thisTarget

The following articles (labelled with PubMed ID or TBD) are for your review

PMID
Data
Article Title
Organization
Pharmacological evaluation and docking studies ofa,ß-unsaturated carbonyl based synthetic compounds as inhibitors of secretory phospholipase A2, cyclooxygenases, lipoxygenase and proinflammatory cytokines.EBI
Universiti Kebangsaan Malaysia
Structural modifications of coumarin derivatives: Determination of antioxidant and lipoxygenase (LOX) inhibitory activity.EBI
TBA
Novel semicarbazides and ureas of primaquine with bulky aryl or hydroxyalkyl substituents: synthesis, cytostatic and antioxidative activity.EBI
University of Zagreb
Synthesis and biological evaluation of salicylic acid and N-acetyl-2-carboxybenzenesulfonamide regioisomers possessing a N-difluoromethyl-1,2-dihydropyrid-2-one pharmacophore: dual inhibitors of cyclooxygenases and 5-lipoxygenase with anti-inflammatory activity.EBI
University of Alberta
New Quinolylnitrones for Stroke Therapy: Antioxidant and Neuroprotective ( Z)- N- tert-Butyl-1-(2-chloro-6-methoxyquinolin-3-yl)methanimine Oxide as a New Lead-Compound for Ischemic Stroke Treatment.EBI
Iqog, Csic
Rational Design of Multitarget-Directed Ligands: Strategies and Emerging Paradigms.EBI
China Pharmaceutical University
Dual antioxidant structures with potent anti-inflammatory, hypolipidemic and cytoprotective properties.EBI
Aristotelian University of Thessaloniki
Azaphenothiazines - promising phenothiazine derivatives. An insight into nomenclature, synthesis, structure elucidation and biological properties.EBI
The Medical University of Silesia
Developing hybrid molecule therapeutics for diverse enzyme inhibitory action: Active role of coumarin-based structural leads in drug discovery.EBI
Abbottabad University of Science and Technology
Substituted pyridines as sodium channel blockersBDB
Purdue Pharma
Pyridone analogs useful as melanin concentrating hormone receptor-1 antagonistsBDB
Bristol-Myers Squibb
Biological profile of the less lipophilic and synthetically more accessible bryostatin 7 closely resembles that of bryostatin 1.BDB
National Cancer Institute-Bethesda
Discovery of a novel class of selective human CB1 inverse agonists.BDB
Vernalis (R&D)