15 articles for thisTarget
The following articles (labelled with PubMed ID or TBD) are for your review
PMID
Data
Article Title
Organization
Turning a Substrate Peptide into a Potent Inhibitor for the Histone Methyltransferase SETD8.
Abbvie
Selective inhibitors of protein methyltransferases.
Icahn School of Medicine At Mount Sinai
Discovery of a selective, substrate-competitive inhibitor of the lysine methyltransferase SETD8.
University of North Carolina At Chapel Hill
Optimization of cellular activity of G9a inhibitors 7-aminoalkoxy-quinazolines.
University of North Carolina At Chapel Hill
Protein lysine methyltransferase G9a inhibitors: design, synthesis, and structure activity relationships of 2,4-diamino-7-aminoalkoxy-quinazolines.
University of North Carolina At Chapel Hill
Discovery of cysteine-targeting covalent histone methyltransferase inhibitors.
Nanjing Medical University
Novel non-covalent LSD1 inhibitors endowed with anticancer effects in leukemia and solid tumor cellular models.
Sapienza University of Rome
Discovery of a potent MLL1 and WDR5 protein-protein interaction inhibitor with in vivo antitumor activity.
China Pharmaceutical University
Structure-Based Design of a Covalent Inhibitor of the SET Domain-Containing Protein 8 (SETD8) Lysine Methyltransferase.
Icahn School of Medicine At Mount Sinai
Design, synthesis, and protein methyltransferase activity of a unique set of constrained amine containing compounds.
The Center For Combinatorial Chemistry and Drug Discovery of Jilin University
Histone methyl transferases: A class of epigenetic opportunities to counter uncontrolled cell proliferation.
Punjabi University
How Selective Are Pharmacological Inhibitors of Cell-Cycle-Regulating Cyclin-Dependent Kinases?
Palack£
Structure-activity relationship studies of SETD8 inhibitors.
Icahn School of Medicine At Mount Sinai
